Synthesis

A practical preparation of 2-carboxyphenylboronic acid and its application for the preparation of biaryl-2-carboxylic acids using suzuki coupling reactions

B Tao, SC Goel, J Singh, DW Boykin

文献索引：Tao, Bin; Goel, Subhash C.; Singh, Jagvir; Boykin, David W. Synthesis, 2002 , # 8 p. 1043 - 1046

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被引用次数: 12

摘要

Abstract A practical synthesis of 2-carboxyphenylboronic from 2-tolylboronic acid and aqueous potassium permanganate under mild conditions is reported. The title compound couples with aryl bromides containing electron-withdrawing groups to give biaryl-2- carboxylic acids.