Organic & biomolecular chemistry

Et 4 NI-catalyzed amidation of aldehydes and alcohols with ammonium salts

G Wang, QY Yu, SY Chen, XQ Yu

文献索引：Wang, Gao; Yu, Qing-Ying; Chen, Shan-Yong; Yu, Xiao-Qi Organic and Biomolecular Chemistry, 2014 , vol. 12, # 3 p. 414 - 417

全文：HTML全文

被引用次数: 22

摘要

An efficient method for the oxidative amidation of benzylic aldehydes or alcohols with ammonium salts has been developed for the synthesis of primary amides using Et4NI as the catalyst and tert-butyl hydroperoxide as the oxidant. This amidation reaction is operationally straightforward and provides primary amides in moderate to good yields under mild conditions.