Synthesis and in vitro characterization of new growth hormone secretagogues derived from ipamorelin with dipeptidomimetic N-terminals

…, K Madsen, H Petersen, H Thøgersen, B Watson

文献索引：Peschke, Bernd; Ankersen, Michael; Sehested Hansen, Birgit; Kruse Hansen, Thomas; Langeland Johansen, Nils; Lau, Jesper; Madsen, Kjeld; Petersen, Hans; Thogersen, Henning; Watson, Brett European Journal of Medicinal Chemistry, 1999 , vol. 34, # 5 p. 363 - 380

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被引用次数: 7

摘要

The structural requirements for N-terminal features for the minimal structure of growth hormone secretagogues derived from ipamorelin are investigated. It is found, that incorporation of nonpolar peptidomimetic amino acids at the N-terminal can replace the ...