Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 2. Syntheses and biological activities of 1, 4-dialkyl-, …
G Le Bihan, F Rondu, A Pelé-Tounian…
文献索引:Journal of Medicinal Chemistry, , vol. 42, # 9 p. 1587 - 1603
... Journal of Medicinal Chemistry. ... 14,15. In a previous paper, 16 we described the syntheses and pharmaceutical evaluation of new antihyperglycemic 1,4-disubstituted-2-(4',5'-dihydro-1'H-imidazol- 2'-yl)- piperazines having the following general formula: These compounds ...
[Matthews, Hayden; Ranson, Marie; Tyndall, Joel D.A.; Kelso, Michael J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 22 p. 6760 - 6766]