Tetrahedron

First stereoselective synthesis of D-amino acid N-alkyl amide catalyzed by D-aminopeptidase

Y Kato, Y Asano, A Nakazawa, K Kondo

文献索引：Kato, Yasuo; Asano, Yasuhisa; Nakazawa, Akiko; Kondo, Kiyosi Tetrahedron, 1989 , vol. 45, # 18 p. 5743 - 5754

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被引用次数: 40

摘要

The first stereoselective synthesis of D-amino acid N-alkyl amides was achieved by the use of D-aminopeptidase from Ochrobactrum anthropi. The enzyme immobilized by urethane prepolymer PU-6 catalyzed aminolysis reaction of racemic amino acid esters in organic solvents.