Abstract The capacity of the nitrogen nucleophile, 1, 8-diazabicyclo [5.4. 0] undec-7-ene (DBU) to reduce aryl-and heteroaryl disulfides to the corresponding mercaptans is demonstrated. While dicarboxylated disulfide analogues afford the mono-DBU disulfide salts, as confirmed by X-ray crystallography, the corresponding methyl esters are cleaved normally. Keywords: Disulfide cleavage, aryl disulfides, DBU, aryl mercaptans
[Grayson, Elizabeth J.; Bernardes, Goncalo J. L.; Chalker, Justin M.; Boutureira, Omar; Koeppe, Julia R.; Davis, Benjamin G. Angewandte Chemie - International Edition, 2011 , vol. 50, # 18 p. 4127 - 4132]
