Tetrahedron Letters

Selective reduction of aldehydes via BINOL–Zr complex

M Lorca, D Kuhn, M Kurosu

文献索引：Lorca, Miguel; Kuhn, Dan; Kurosu, Michio Tetrahedron Letters, 2001 , vol. 42, # 36 p. 6243 - 6246

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被引用次数: 14

摘要

An easily assembled catalyst from (±)-BINOL (1, 1′-bi-naphthol) and Zr (OiPr) 4· iPrOH selectively reduces aldehydes at room temperature. Ketones remain intact under these conditions. A catalytic amount of BINOL–Zr complex in the presence of 2-propanol also effectively reduces a variety of chiral and achiral aldehydes.