Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines

S Rault, JC Lancelot, H Prunier, M Robba…

文献索引：Journal of Medicinal Chemistry, , vol. 39, # 10 p. 2068 - 2080

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被引用次数: 63

摘要

... Journal of Medicinal Chemistry. ... Introduction. Fifty years after its discovery by Page 1 and Erspamer, 2 serotonin (5-hydroxytryptamine, 5-HT) remains one of the most attractive targets for medicinal chemists. 5-HT ... Chemistry. The general ...