A structure–permeability study of small drug-like molecules

T Fichert, M Yazdanian, JR Proudfoot

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 4 p. 719 - 722

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被引用次数: 55

摘要

... Bioorganic & Medicinal Chemistry Letters. ... used the Caco-2 cell model to evaluate the cell permeability of peptidomimetic carboxylic acid derivatives designed as ligands for the p56lck SH2 domain, 3 and found that the data was useful in guiding medicinal chemistry efforts to ...