α-Bromoacid Amides and Ureas as Anticonvulsants

SR Safir, H Dalalian, W Fanshawe, K Cyr…

文献索引：Safir et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 4840,4842

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被引用次数: 11

摘要

-1lthough a-bromoamides and ureas have for many years been used in medicine as sedatives and hypnotics, no systematic survey of this class of drugs for anticonvulsant potentiality appears to have been made.'The finding that neuronal (I) and carbromal (11) exhibited a high degree of protection against metrazole-induced seizures in rats gave impetus to the hope that a drug useful in petit mal epilepsy might be found in the class of ...