Tetrahedron: Asymmetry

Palladium catalyzed asymmetric sulfonylation mediated chiral β-hydroxy-and β-(o-diphenylphosphino) benzoyloxy (o-diphenyl phosphino) benzamides

JA Wolfe, SR Hitchcock

文献索引：Wolfe, Jesse A.; Hitchcock, Shawn R. Tetrahedron Asymmetry, 2010 , vol. 21, # 21-22 p. 2690 - 2695

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被引用次数: 7

摘要

The palladium catalyzed asymmetric allylic sulfonylation reaction has been investigated employing β-hydroxy-and β-(o-diphenylphosphino) benzoyloxy (o-diphenyl phosphino) benzamides as chiral, non-racemic ligands. The bisphosphine β-benzoyloxybenzamide ligands proved to be the best ligands for this process. Competitive transition states for the (1S, 2R)-norephedrine derived ligand 14 are compared and a rationale is provided for the ...