Cyclization reactions mediated by palladium (intramolecular Heck reaction) or radical initiators would be very useful in combinatorial chemistry. Both processes are complementary. They are feasible from the same starting material (aromatic or vinylic iodides, bromides carrying an unsaturated chain) leading to cyclized products with different oxidation states. The palladium-mediated reaction would deliver the unsaturated product. In contrast, radical cyclization mediated by ...
