The Journal of organic chemistry

Preparation of nonsymmetrically substituted stilbenes in a one-pot two-step Heck strategy using ethene as a reagent

CM Kormos, NE Leadbeater

文献索引：Kormos, Chad M.; Leadbeater, Nicholas E. Journal of Organic Chemistry, 2008 , vol. 73, # 10 p. 3854 - 3858

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被引用次数: 38

摘要

We present here a strategy for the preparation of nonsymmetrically substituted stilbenes using a one-pot two-step double Heck strategy. First a protocol is developed for the selective preparation of a range of styrenes using ethene as the alkene coupling partner. Then conditions are found for the effective coupling of the styrenes with aryl halides using a 1: 1 stoichiometric ratio of the two components. The use of the microwave apparatus to perform ...