... The remaining SYNTHESIS bromide solution is added over 45 min at 30" C. The Grignard reagent solution is transferred (via cannula and addition funnel) to a stirred solution of trimethyl borate (68 mL, 0611101) in THF (200 mL) at ~ 10 'C ... (12) Fiauid, FC ... P., Chatelus, GCR Acad ...