The selective protection of uridine with a p-methoxybenzyl chloride: a synthesis of 2'-O-methyluridine

T Akiyama, H Nishimoto, S Ozaki

文献索引：Akiyama; Nishimoto; Ozaki Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 11 p. 3356 - 3357

被引用次数: 20

摘要

Résumé/Abstract 2'-O-Methyluridine was prepared through 5 steps from uridine by use of p- methoxybenzyl groupe (PMB) as an N 3-protecting group of uridine. A chemoselective protection method has been developed by use of DBU as a base and deprotection was effected by AlCl 3-anisole system

~79%

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