Oligodeoxyribonucleotide synthesis by use of S, S-diphenyl deoxyribonucleoside 3'-phosphorodithioates and bifunctional condensing reagents in the phosphotriester …
Four kinds of arenedisulphonyl chlorides as condensing reagents for oligodeoxyribonucleotide synthesis have been synthesised and their condensing abilities were examined in the synthesis of thymidylyl (3'-5') thymidine. Among them, mesitylenedisulphonyl chloride (MDS) and isodurenedisulphonyl chloride (DDS) proved to be effective for condensation and for separation of the product from the 5'-sulphonated by- ...
