The Interaction of Trihalogenoacetic Anhydrides and Trihalogenoacetyl Chlorides with Thymidine 5"-Phosphate as an Approach to New Activating Agents in the …
VS Bogachev, PA Ulanov
文献索引：Bogachev; Ulanov Russian Journal of Bioorganic Chemistry, 2003 , vol. 29, # 1 p. 56 - 65
Abstract The interaction of thymidine 5"-phosphate with trichloroacetic anhydride, trichloroacetyl chloride, and tribromoacetyl bromide was studied in dimethylformamide and acetonitrile in the presence of tertiary amines. The first two reactions gave the mixed anhydride of trichloroacetic and thymidylic acids (acyl phosphate) as the major product and P 1, P 2-dithymidine 5"-pyrophosphate as the byproduct. The third reaction proceeded by ...
