Metal-free artificial nucleases based on simple oxime and hydroxylamine scaffolds

L Fernandes, FL Fischer, CW Ribeiro…

文献索引：Fernandes, Luciano; Fischer, Franciele L.; Ribeiro, Carolina W.; Silveira, Gustavo P.; Sa, Marcus M.; Nome, Faruk; Terenzi, Hernan Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 16 p. 4499 - 4502

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被引用次数: 15

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Hydrolysis of DNA is of increasing importance in biotechnology and medicine. In this Letter, we present the DNA-cleavage potential of metal-free hydroxylamines and oximes as new members of nucleic acid cleavage agents. ... Hydrolysis of DNA is of increasing importance in biotechnology ...