Synthesis and assembly of poly (ethylene glycol)-lipids with mono-, di-, and tetraacyl chains and a poly (ethylene glycol) chain of various molecular weights
S Takeoka, K Mori, H Ohkawa, K Sou…
文献索引:Takeoka, Shinji; Mori, Katsura; Ohkawa, Haruki; Sou, Keitaro; Tsuchida, Eishun Journal of the American Chemical Society, 2000 , vol. 122, # 33 p. 7927 - 7935
We synthesized a series of amphiphiles with poly (ethylene glycol)[MW 2000 (PEG20), 5000 (PEG50), 12 500 (PEG125)] as a headgroup and one, two, or four palmitoyl chains (1C16, 2C16, or 4C16), using a lysine monodendron as a connector. The relationship between the hydrophilic-hydrophobic balance of the multiacyl PEG-lipids and the physicochemical characteristics in self-or co-assembly with phospholipids were studied. The PEG-lipids ...