Syntheses of resveratrol and its hydroxylated derivatives as radical scavenger and tyrosinase inhibitor

HS Lee, BW Lee, MR Kim, JG Jun

文献索引：Lee, Hyun Suck; Lee, Byung Won; Kim, Mi Ran; Jun, Jong-Gab Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 4 p. 971 - 975

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被引用次数: 16

摘要

Abstract Eight hydroxylated stilbene derivatives including resveratrol, desoxyrhapontigenin and piceatannol as potential radical scavenger and tyrosinase inhibitor are synthesized using optimized Wittig-Horner reaction for excellent trans-selectivity in good yields. Antioxidant activity was tested against ABTS radical and tyrosinase inhibitory activity was performed with L-tyrosine as the substrate based on previous procedure with some ...