Highly selective oxidative monochlorination to synthesize organic intermediates: 2-Chlorotoluene, 2-chloroaniline, 2-chlorophenol, and 2-chloro-4-methylphenol

S Mukhopadhyay, KH Chandnani…

文献索引：Mukhopadhyay, Sudip; Chandnani, Kavita H.; Chandalia, Sampatraj B. Organic Process Research and Development, 1999 , vol. 3, # 3 p. 196 - 200

全文：HTML全文

被引用次数: 10

摘要

An alternative manufacturing process scheme was developed to synthesize monochloro- substituted aromatic compounds in high selectivity, involving oxidative chlorination by using HCl-H2O2. Thus, 2-chlorotoluene, 2-chloroaniline, and 2-chlorophenol were synthesized by oxidative chlorination followed by desulphonation or decarboxylation. Oxidative chlorination of 4-methylbenzenesulphonic acid, 4-methylbenzoic acid, 4-aminobenzoic acid, and 4- ...