Tetrahedron letters

Synthesis of N-substituted 1, 2, 5-thiadiazolidine and 1, 2, 6-thiadiazinane 1, 1-dioxides from primary amines

PD Johnson, SA Jewell, DL Romero

文献索引：Johnson, Paul D.; Jewell, Sarah A.; Romero, Donna L. Tetrahedron Letters, 2003 , vol. 44, # 29 p. 5483 - 5485

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被引用次数: 7

摘要

Alkyl and aryl N-substituted 1, 2, 5-thiadiazolidine and 1, 2, 6-thiadiazinane 1, 1-dioxides 6 were synthesized in good yields from the reaction of sulfuryl chloride with 2- chloroethylamine or 3-chloropropylamine hydrochlorides, respectively, followed by treatment with a primary amine and triethylamine, and ring closure with K2CO3 in DMSO.