Journal of the American Chemical Society

Synthesis of Indole-3-acetic Acids and 2-Carboxyindole-3-acetic Acids with Substituents in the Benzene Ring1

SW Fox, MW Bullock

文献索引：Fox; Bullock Journal of the American Chemical Society, 1951 , vol. 73, p. 2756,2758

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被引用次数: 26

摘要

A number of indole-3-acetic acids with substituents in the benzene ring have been prepared by the Fischer cyclization of corresponding succinaldehydic acid phenylhydrazones which were in turn prepared by the sequence of reactions: glutamic. itid 6 succinaldehydic acid+ succinaldehydic acid phenylhydrazone. The 4-and 6-chloroindole-3-acetic acids have also heen synthesized by condensation of the corresponding indolylmagnesium iodide ...