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Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S, S)-5]

F Bennett, AK Saksena, RG Lovey, YT Liu…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 1 p. 186 - 190

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被引用次数: 27

摘要

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Similarly, using the chemistry described in Scheme 1 and (d)-lactate as starting material, (R,R)-5 and (R,S)-5 can be synthesized. ...