Synthesis of nitroxyl (aminoxyl) labeled probes for studies of intracellular environment by EPR and MRI

G Sosnovsky, NUM Rao, SW Li…

文献索引：Sosnovsky, George; Rao, Nuti Uma Maheswara; Li, Shu Wen; Swartz, Harold M. Journal of Organic Chemistry, 1989 , vol. 54, # 15 p. 3667 - 3674

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被引用次数: 39

摘要

Synthesa are delineated for the following three classes of nitroxyl (aminoxyl) labeled active esters:(1) phosphoric acid derivatives containing phenyl and p-nitrophenyl moieties,(2) EDTA and DTPA containing acetoxymethyl and (pivaloy1oxy) methyl as protecting groups, and (3) several amino acid derivatives containing the acetoxymethyl group. These compounds are expected to be of interest as potential probes in studies of intracellular ...