Tetrahedron

One-pot efficient synthesis of aryl α-keto esters from aryl-ketones

J Zhuang, C Wang, F Xie, W Zhang

文献索引：Zhuang, Jing; Wang, Changqing; Xie, Fang; Zhang, Wanbin Tetrahedron, 2009 , vol. 65, # 47 p. 9797 - 9800

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被引用次数: 19

摘要

In the past several decades, there was much attention fixed on the synthesis of α-keto esters. Several routes were reported including oxidation of α-hydroxy esters with either PCC or Dess–Martin periodinane, 7, 7a and 7b Friedel–Crafts acylation, 8 oxidative cleavage of cyano keto phosphoranes, 9 hydrolysis and esterification of acyl cyanides, 4 the reaction of organometallic species with oxalic ester derivatives, 10 and acylation or alkylation of mono-substituted ...