Abstract Sulfonyl hydrazides and sulfonyl semicarbazides are readily prepared by the reacting of hydrazine derivatives with sulfonyl chlorides in the presence of basic alumina under solvent-free conditions. Reaction of a sulfonyl chloride with t-butylcarbazate, followed by hydrolysis provides the corresponding sulfonyl hydrazides in higher yield and shorter time than previously reported.
![N-[4-(hydrazinesulfonyl)phenyl]acetamide结构式](https://image.chemsrc.com/caspic/022/3989-50-2.png)
