Soft Matter

An algorithm to determine the mechanism of drug distribution in lipid-core nanocapsule formulations

…, B Donida, FS Poletto, SS Guterres, AR Pohlmann

文献索引：Oliveira, Catiuscia P.; Venturini, Cristina G.; Donida, Bruna; Poletto, Fernanda S.; Guterres, Silvia S.; Pohlmann, Adriana R. Soft Matter, 2013 , vol. 9, # 4 p. 1141 - 1150

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被引用次数: 34

摘要

Aqueous solutions of lipid-core nanocapsules are interesting drug delivery systems for passive drug targeting. In this study, we hypothesized that the drug distribution mechanisms in lipid-core nanocapsule formulations could be categorized into six different types. To experimentally determine the type of drug distribution in these formulations, we proposed the use of an algorithm as an innovative strategy. The approach is shown to be a valuable ...