Organic & biomolecular chemistry

Preparation of fluoxetine by multiple flow processing steps

B Ahmed-Omer, AJ Sanderson

文献索引：Ahmed-Omer, Batoul; Sanderson, Adam J. Organic and Biomolecular Chemistry, 2011 , vol. 9, # 10 p. 3854 - 3862

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被引用次数: 16

摘要

Microflow technology is established as a modern and fashionable tool in synthetic organic chemistry, bringing great improvement and potential, on account of a series of advantages over flask methods. The study presented here focuses on the application of flow chemistry process in performing an efficient multiple step syntheses of (±)-fluoxetine as an alternative to conventional synthetic methods, and one of the few examples of total synthesis ...