Over the past 10 years chiral a-amino aldehydes have become very popular as synthetic precursors of biologically active molecules.'In this paper, we report on the stereoselective aldol reactions involving chiral NJV-diprotected a-amino aldehydes and chiral boron enolates. 2 The aldol reaction between an acetate-derived enolate and a chiral aldehyde creates a new stereogenic center and two possible diastereoisomers (Scheme 1). In ...
