Tetrahedron Letters

Synthesis of the C1 C9 segment of epothilons

E Claus, A Pahl, PG Jones, HM Meyer, M Kalesse

文献索引：Claus, Eckhard; Pahl, Axel; Jones, Peter G.; Meyer, Hartmut M.; Kalesse, Markus Tetrahedron Letters, 1997 ,  vol. 38,  # 8  p. 1359 - 1362

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被引用次数: 74

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The C1C9 segment of epothilons was generated by an aldol reaction between chiral aldehyde 3 and ethyl ketone 4. Removal of the TBS protecting groups and debenzylation generated spiro ketal 13 which was analyzed by X-ray crystallography. ... Aldol reaction of key fragments ...