Total synthesis of the ravidomycin aglycone (defucogilvocarcin V)

JA Findlay, A Daljeet, PJ Murray…

文献索引：Findlay, John A.; Daljeet, Anand; Murray, Peter John; Rej, Rabindra N. Canadian Journal of Chemistry, 1987 ,  vol. 65, p. 427 - 431

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被引用次数: 25

摘要

The synthesis of 1-hydroxy-10, 12-dimethoxy-8-vinyl-6 H-benzo [d] naphtho [1, 2 b] pyran-6- one 7, starting from vanillin and 1, 5-dihydroxynaphthalene is described. This compound is the aglycone of the antitumor antibiotic ravidomycin and is identical with the recently reported antimicrobial agent, defucogilvocarcin V.