The oxidation of 6??and 7??aryl??4 (3h)??pteridinones by immobilized arthrobacter M??4 cells containing xanthine oxidase

…, HC Van Der Plas, WJ Middelhoven

文献索引：Meester, Johan W. G. De; Plas, Henk C. van der; Middelhoven, Wouter J. Journal of Heterocyclic Chemistry, 1987 ,  vol. 24, p. 441 - 451

全文：HTML全文

被引用次数: 14

摘要

Abstract The preparation of 6-and 7-(pX-phenyl)-4 (3H)-pteridinones (X= H, CH 3, OCH 3) is described. The oxidation of these compounds by (immobilized) Arthrobacter M-4 cells containing xanthine oxidase has been studied. The oxidation monitored by uv spectroscopy usually goes fast, except for 7-(pX-phenyl)-4 (3H)-pteridinones (X= CH 3, OCH 3), which are slowly oxidized. With bacterial cells immobilized in gelatine crosslinked with ...