The Schiff bases, N-(S-guaiazulen-3-ylmethylene) cyclohexylamine (II), N-(S-guaiazulen-3- ylmethylene) benzylamine (III), and N-(S-guaiazulen-3-ylmethylene)-1, 1-dimethyl-2- hydroxyethylamine (IV) were prepared in excellent yields by condensation of S-guaiazulene- 3-carboxaldehyde (I) with corresponding primary amines. These bases were easily converted into secondary amino derivatives of S-guaiazulene, ie 3- ...