A synthetic study on antiviral and antioxidative chromene derivative

J Mori, M Iwashima, M Takeuchi, H Saito

文献索引：Mori, Jun; Iwashima, Makoto; Takeuchi, Makoto; Saito, Haruo Chemical and Pharmaceutical Bulletin, 2006 ,  vol. 54,  # 3  p. 391 - 396

全文：HTML全文

被引用次数: 43

摘要

An efficient synthesis of the antiviral and antioxidative chromene (1) was achieved. A small amount of chromene 1 could be derived from plastoquinones 2 and 3, the major constituents of the brown alga, Sargassum micracanthum. By the following synthetic scheme involving its application, many kinds of analogs can be synthesized for evaluation of their biological activity and mechanistic study. The total synthesis of 1, started from geranyl acetate and ...