Inhibitors of the fungal cell wall. Synthesis of 4-aryl-4-N-arylamine-1-butenes and related compounds with inhibitory activities on β (1–3) glucan and chitin synthases
…, JCG Cortés, A Palma, SN López, SA Zacchino…
文献索引：Urbina, Juan M.; Cortes, Juan C. G.; Palma, Alirio; Lopez, Silvia N.; Zacchino, Susana A.; Enriz, Ricardo D.; Ribas, Juan C.; Kouznetzov, Vladimir V. Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 4 p. 691 - 698
As part of our project devoted to the search for antifungal agents, which act via a selective mode of action, we synthesized a series of new 4-aryl-or 4-alkyl-N-arylamine-1-butenes and transformed some of them into 2-substituted 4-methyl-tetrahydroquinolines and quinolines by using a novel three-step synthesis. Results obtained in agar dilution assays have shown that 4-aryl homoallylamines not possessing halogen in their structures, ...
