Synlett

Cu-FeCl3-mediated one-pot multicomponent reaction leading to N-aryl-and N-alkyltriazoles in water

B Saha, S Sharma, D Sawant, B Kundu

文献索引：Saha, Biswajit; Sharma, Sunil; Sawant, Devesh; Kundu, Bijoy Synlett, 2007 , # 10 p. 1591 - 1594

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被引用次数: 27

摘要

Abstract A concise, convenient and mild route for the one-pot syntheses of N-aryl-and N- alkyltriazoles in water is reported. The methodology involves the three-component reaction comprising phenylacetylene, sodium azide and aryl/alkyl halide catalyzed by Cu (I) species generated in situ by a redox reaction between FeCl 3 and copper metal. Prominent features of our methodology are incorporation of aryl fluoride to generate N-aryltriazoles, which are ...