Synthetic communications

An Efficient Procedure for the Synthesis of Benzimidazole Derivatives Using Yb (OTf) 3 as Catalyst Under Solvent??Free Conditions

L Wang, J Sheng, H Tian, C Qian

文献索引：Wang, Limin; Sheng, Jia; Tian, He; Qian, Changtao Synthetic Communications, 2004 , vol. 34, # 23 p. 4265 - 4272

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被引用次数: 42

摘要

Abstract o??Diaminobenzene derivatives react smoothly with ortho??esters in the presence of 0.5 mol% of Yb (OTf) 3 under solvent??free conditions to afford the corresponding benzimidazole derivatives in good to excellent yields. In addition, Yb (OTf) 3 can be easily recovered almost quantitatively from the aqueous layer after the reaction was completed, and it could be reused with no loss of activity.