The Journal of organic chemistry

An efficient carbene-catalyzed access to 3, 4-dihydrocoumarins

K Zeitler, CA Rose

文献索引：Zeitler, Kirsten; Rose, Christopher A. Journal of Organic Chemistry, 2009 , vol. 74, # 4 p. 1759 - 1762

全文：HTML全文

被引用次数: 61

摘要

Dihydrocoumarins play an important role as flavor and fragrance compounds and can be prepared efficiently from o-hydroxycinnamaldehydes in a mild, atom-economic N- heterocyclic carbene-catalyzed redox lactonization. Corresponding coumarins are accessible via a one-pot domino oxidation lactonization procedure in the presence of oxidants.