Bioscience, biotechnology, and biochemistry

Substrate specificity and regioselectivity of Δ12 and ω3 fatty acid desaturases from Saccharomyces kluyveri

T Oura, S Kajiwara

文献索引：Oura, Takahiro; Kajiwara, Susumu Bioscience, Biotechnology and Biochemistry, 2008 , vol. 72, # 12 p. 3174 - 3179

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被引用次数: 8

摘要

Δ12 and ω3 fatty acid desaturases are key enzymes in the synthesis of polyunsaturated fatty acids (PUFAs), which are important constituents of membrane glycerolipids and also precursors to signaling molecules in many organisms. In this study, we determined the substrate specificity and regioselectivity of the Δ12 and ω3 fatty acid desaturases from Saccharomyces kluyveri (Sk-FAD2 and Sk-FAD3). Based on heterologous expression in ...