Tetrahedron letters

Isochroman-3-ones via site-selective ring opening of benzocyclobutenones promoted by lithium tetramethylpiperidide and reaction with aromatic aldehydes

T Matsumoto, T Hamura, Y Kuriyama, K Suzuki

文献索引：Matsumoto, Takashi; Hamura, Toshiyuki; Kuriyama, Yokusu; Suzuki, Keisuke Tetrahedron Letters, 1997 , vol. 38, # 52 p. 8985 - 8988

全文：HTML全文

被引用次数: 18

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... In the presence of Li-TMP and an aromatic aldehyde, benzocyclobutenone undergoes an unusual heterolytic C(1)C(4) bond fission, and subsequent reaction with the aldehyde gives, after acidic workup, isochroman-3-one in high yield. ... A synthetic method of isochroman-3-one from ...