Tetrahedron Letters

One-pot catalytic C–C double bond cleavage of α, β-enones aided by alkyl group-immobilized silica spheres

DH Lee, EA Jo, JW Park, CH Jun

文献索引：Lee, Dong Hun; Jo, Eun-Ae; Park, Jung-Woo; Jun, Chul-Ho Tetrahedron Letters, 2010 , vol. 51, # 1 p. 160 - 163

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被引用次数: 10

摘要

Catalytic C–C double bond cleavage of α, β-enones with a 1-alkene and H2O was carried out in the presence of a (Ph3P) 3RhCl catalyst, 2-amino-3-picoline, cyclohexylamine, benzoic acid, and alkyl group-immobilized silica spheres. Upon completion of the reaction, the corresponding ketones were obtained without needing a further hydrolysis step. In this reaction, alkyl group-immobilized silica spheres act as a water reservoir for hydrolysis of ...