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Functional fluorescence labeling of carbohydrates and its use for preparation of neoglycoconjugates

K Fukase, H Nakayama, M Kurosawa…

文献索引:Fukase, Koichi; Nakayama, Hideo; Kurosawa, Motohiro; Ikegaki, Toshiki; Kanoh, Takeshi; et al. Journal of Carbohydrate Chemistry, 1994 , vol. 13, # 5 p. 715 - 736

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被引用次数: 16

摘要

Abstract New bifunctional reagents, 2-amino-6-carboxyethylpyridine and 2-amino-6- cyanoethylpyridine, were designed and synthesized in order to provide a novel procedure for preparation of neoglycoconjugates from fluorescence-labeled and purified sugar chains. Labeling of model sugar chains with these reagents was effected by reductive amination using BH3. Me2NH to give corresponding 6-carboxyethylpyridylaminated (CEPA-) and 6- ...