New class of sympathetic. beta.-receptor blocking agents. 3, 4-Dihydro-3-hydroxy-1, 5-benzoxazocines

B Basil, ECJ Coffee, DL Gell, DR Maxwell…

文献索引：Basil,B. et al. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 403 - 406

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被引用次数: 26

摘要

Arzeim. Forsrh., 18, 48 (1968); PN Patil, A. Tye, and JB LaPidns, J. Pharmacal Exp. Ther., 166,445 (1967). cological properties eg,@-blocking, quinidine-like, local anesthetic, and possibly hypotensive properties,* and we considered the possibility of synthesizing structures in which the mobility of the side chain was restricted in the hope of achieving some specificity of pharmacological action. One approach entailed linking the side chain ...