Azole Series. II. Reactions of 2-Acylamino-2-cyanoacetamides leading to 5-Acylaminooxazole-4-carboxamides and to Oxazolo [5, 4-d] pyrimidines

M SEKIYA, J SUZUKI, Y KAKIYA

文献索引：Sekiya,M. et al. Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1233 - 1238

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被引用次数: 7

摘要

Reaction for preparation of a new series of 5-acylaminooxazole-4-carboxamides has been found. 5-Acetamidooxazole-4-carboxamides were obtained by heating 2-acylamino-2- cyanoacetamides with acetic anhydride in the presence of perchloric acid. Analogous 5-form- amido derivatives were also obtained by heating the same substrates with a mixture of formic acid and acetic anhydride in the presence of hydrochloric acid. Trials for synthesis ...