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Formation of aziridinones (α-lactams) from hydroxamic derivatives

CM Bladon, GW Kirby

文献索引:Bladon; Kirby Journal of the Chemical Society, Chemical Communications, 1982 , p. 1402

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被引用次数: 0

摘要

Various NO-disubstituted derivatives of chloroaceto- and phenylaceto-hydroxamic acid are shown to cyclise with base to give aziridinones with cleavage of the N-0 bond, a process exemplified by an efficient synthesis of I -t-butyl-3-phenylaziridin-2-one. ... Thebaine (1 ; R -- Me) readily forms cycloadducts [as (2)] with transient nitrosocarbonyl compounds generated ir2 situ by ... Published on 01 January 1982. Downloaded by google on 26/04/2016 09:42:36.