The Journal of organic chemistry

Effects of olefin substitution on the ring-closing metathesis of dienes

TA Kirkland, RH Grubbs

文献索引：Kirkland, Thomas A.; Grubbs, Robert H. Journal of Organic Chemistry, 1997 , vol. 62, # 21 p. 7310 - 7318

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被引用次数: 266

摘要

Ruthenium alkylidene 1 and molybdenum alkylidene 2 have been utilized in the ring-closing metathesis (RCM) of dienes containing gem-disubstituted olefins to yield tri-and tetrasubstituted cyclic olefins. Dienes with sterically demanding and/or electron-withdrawing substituents such as Ph, CO2Me, and t Bu were cyclized successfully with 2, but did not cyclize with 1. Tetrasubstituted cyclic olefins could be formed with 2, but not using ...