The Journal of Organic Chemistry

The Preparation of α, α-Dichloro Ketones1

SF Reed Jr

文献索引：Reed,S.F. Journal of Organic Chemistry, 1965 , vol. 30, p. 2195 - 2198

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被引用次数: 29

摘要

A novel method for the preparation of a, a-dichloro ketones has been found involving the reaction of acetylenes with N-chlorosuccinimide in methanol to give the dihalodimethyl ketals which are readily hydrolyzed with dilute acid to the ketones. The scope of the reaction appears to be of a general nature giving the ketones in 6040% yields. The products were characterized by their proton nmr spectra.