A new method for synthesis of unsymmetrical ureas using electrochemically prepared trifluoroethyl carbamates

Y Matsumura, Y Satoh, O Onomura…

文献索引：Matsumura, Yoshihiro; Satoh, Yuki; Onomura, Osamu; Maki, Toshihide Journal of Organic Chemistry, 2000 , vol. 65, # 5 p. 1549 - 1551

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被引用次数: 31

摘要

Substituted ureas have attracted much attention because of their important biological activities, 1 and thus there have been a variety of the synthetic methods. 2 However, most of the methods are limited to the preparation of symmetrical ureas and have the drawback that highly toxic reagents such as phosgene must be used. On the other hand, some methods applicable to the preparation of unsymmetrical ureas 1 without the use of any toxic ...