Tetrahedron Letters

Hydrophilic cholesterol-binding molecular imprinted polymers

N Zhong, HS Byun, R Bittman

文献索引：Zhong, Ning; Byun, Hoe-Sup; Bittman, Robert Tetrahedron Letters, 2001 , vol. 42, # 10 p. 1839 - 1841

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被引用次数: 51

摘要

Novel hydrophilic molecularly imprinted polymers (MIPs) were prepared using acryloyl- containing hydrophilic monomers (including cholesteryl acrylate (CA) and acryloyl-6-amino- 6-deoxy-β (or γ)-cyclodextrin), and their steroid-binding properties were analyzed in 2-PrOH by HPLC. The MIPs bound 38–50 μmol of cholesterol/g, while the corresponding nonimprinted control polymers (containing no CA) bound only 6–9 μmol cholesterol/g. The ...